Chemical Synthesis


The primary focus is in synthesizing various molecules showing promising pharmacological activity with minimal toxicity and maximum efficacy. We are actively involved in the below mentioned activities

  • Hit and lead development in various therapeutic areas such as Antifungal, Oncology, metabolic disorders, Alzheimer’s disease, Inflammatory diseases
  • Chemistry services integrated with biological profiling
  • Structure based designing of compound libraries, plant based compounds
  • Green chemistry
  • Process improvements

Research Topics

  • Different approaches for rational drug design with understanding of the therapeutic pathways at molecular level 
  • Concepts of QSAR and molecular modelling for computational drug design 
  • Chemistry of medicinal compounds from natural sources 
  • Methods of structural elucidation for Lead identification and Optimization
  • Development and optimization of synthetic route/​s and the pilot plant procedure for manufacture of APIs and NCEs

We have a list of equipment’s required for chemical synthesis and analysis includes HPLC, HPTLC, FT-IR etc

  • Rotary flash evaporator
  • Cooling Centrifuge

Being Created

  • We intend to procure other equipments/​instruments depending on the requirement.


  • Journal of Medicinal Chemistry
  • Current Medicinal Chemistry
  • Bioorganic and Medicinal Chemistry
  • European Journal of Medicinal Chemistry
  • Current Topics in Medicinal Chemistry
  • Current Medicinal Chemistry — Anti-Cancer Agents
  • Mini-Reviews in Medicinal Chemistry
  • Journal of Enzyme Inhibition and Medicinal Chemistry


  • Discovery of Anti-COVID19 Agents from Indian Medicinal Plant Constituents through the Application of in silico Molecular Docking Studies
  • Chemo Preventive Effect of Natural Constituents Against Breast Cancer: Application of Molecular Modelling Studies
  • Discovery of Anti-Malarial Agents from Indian Medicinal Plant Constituents Through the Application of in silico Molecular Docking Studies
  • Design, Molecular Docking, Synthesis, Pharmacological Evaluation, In Vitro Stability and Protein Binding Studies of Novel Benzimidazole Derivatives
  • Synthesis, Formulation and Pharmacological evaluation of 2,5 dihydroxybenzaldehyde for Cardioprotective activity by inhibiting Rho kinase in rats
  • Design, Synthesis, Characterization and Pharmacological evaluation of some novel heterocyclic compounds against Alzheimer’s disease: Application of molecular modelling studies

Drug Design and Development Centre,
Faculty of Pharmacy, M.S.Ramaiah University of Applied Sciences,
Gnanagangothri Campus, New BEL Road, Bangalore -560054
Ph: 080-23608942 Extn:29, 9880238650
Email: email hidden; JavaScript is required
Dr. Suma B Venkatappa Dr. Parasuraman P Ms. Knolin K Thachil Dr. Vijaybhanu Perumalsamy