Chemical Synthesis
Overview
The primary focus is in synthesizing various molecules showing promising pharmacological activity with minimal toxicity and maximum efficacy. We are actively involved in the below mentioned activities
- Hit and lead development in various therapeutic areas such as Antifungal, Oncology, metabolic disorders, Alzheimer’s disease, Inflammatory diseases
- Chemistry services integrated with biological profiling
- Structure based designing of compound libraries, plant based compounds
- Green chemistry
- Process improvements
Research Topics
- Different approaches for rational drug design with understanding of the therapeutic pathways at molecular level
- Concepts of QSAR and molecular modelling for computational drug design
- Chemistry of medicinal compounds from natural sources
- Methods of structural elucidation for Lead identification and Optimization
- Development and optimization of synthetic route/s and the pilot plant procedure for manufacture of APIs and NCEs
We have a list of equipment’s required for chemical synthesis and analysis includes HPLC, HPTLC, FT-IR etc
- Rotary flash evaporator
- Cooling Centrifuge
Being Created
- We intend to procure other equipments/instruments depending on the requirement.
Journals
- Journal of Medicinal Chemistry
- Current Medicinal Chemistry
- Bioorganic and Medicinal Chemistry
- European Journal of Medicinal Chemistry
- Current Topics in Medicinal Chemistry
- Current Medicinal Chemistry — Anti-Cancer Agents
- Mini-Reviews in Medicinal Chemistry
- Journal of Enzyme Inhibition and Medicinal Chemistry
Projects
- Discovery of Anti-COVID19 Agents from Indian Medicinal Plant Constituents through the Application of in silico Molecular Docking Studies
- Chemo Preventive Effect of Natural Constituents Against Breast Cancer: Application of Molecular Modelling Studies
- Discovery of Anti-Malarial Agents from Indian Medicinal Plant Constituents Through the Application of in silico Molecular Docking Studies
- Design, Molecular Docking, Synthesis, Pharmacological Evaluation, In Vitro Stability and Protein Binding Studies of Novel Benzimidazole Derivatives
- Synthesis, Formulation and Pharmacological evaluation of 2,5 dihydroxybenzaldehyde for Cardioprotective activity by inhibiting Rho kinase in rats
- Design, Synthesis, Characterization and Pharmacological evaluation of some novel heterocyclic compounds against Alzheimer’s disease: Application of molecular modelling studies
Contact
- Address
- Drug Design and Development Centre,
Faculty of Pharmacy, M.S.Ramaiah University of Applied Sciences,
Gnanagangothri Campus, New BEL Road, Bangalore -560054
Ph: 080-23608942 Extn:29, 9880238650
Email: email hidden; JavaScript is required - Person
- Dr. Suma B Venkatappa Dr. Parasuraman P Ms. Knolin K Thachil Dr. Vijaybhanu Perumalsamy