Drug Design & Development Centre


  • Research Head

    Dr. Deveswaran R

Overview

Drug Design and Development Centre (DDDC) is a dedicated centre focusing on Research and Development in Pharmaceutical Sciences. The main domain includes Drug Design, Pharmacological Screening, Analytical Method Development, Formulation Development and Stability Studies for Herbal, Intermediates and Synthetic Drugs. DDDC can able to cater to the needs of pharmaceutical industry. We also intend to develop future pharmacists with the required skills and capabilities, support PG, UG and Ph.D Research scholars towards their research activities. The members of DDDC actively contribute to quality research publications, presentations at various National and International seminars, filing of patents etc, thereby actively participating in the centre activities. 

Vision

To develop safe and efficacious drug products for patient benefit

Proposed Research works

  • Design and Development of Wound dressings with sensor
  • Design and Development of plantain leaf extract/​juice/​powder for treating burns as first aid
  • Development of clotrimazole emulgel for topical application
  • Development of Curcumin with silver sulphadiazine gel/​paste for wound/​burns
  • Improvement of aqueous solubility of poorly water soluble drugs
  • Developing flexible foams/​sponges to arrest bleeding immediately
  • ● Development of taste masked paracetamol granules in sachet

Projects

Consultancy works completed

Title of the work

Name of the Company

Antiseptic liquid bandage

ITC Ltd, Bangalore

Nicotine nasal insert

ITC Ltd, Bangalore

Increased drug release from Nicotine chewing gum

ITC Ltd, Bangalore

Development of phosphatidyl choline cream

Lyrus Life Sciences, Bangalore

Personal care products

Lyrus Life Sciences, Bangalore

Improvement of dissolution of Telmisartan with Hydrochlorothiazide, Telmisartan with amlodipine and Metformin hydrochloride with Glimepiride as per Indian Pharmacopoeia 2018 specifications. 

LifeCare Formulations

Pvt. Ltd Puducherry

Taste masking of multivitamin and amino acids granules 

LifeCare Formulations

Pvt. Ltd Puducherry

Determination of surface tension of processed water and its stability

NanoWaters, Aruthra Products, Bangalore

Phytochemical analysis of plant extracts

Auxochromofours Solutions Pvt.Ltd, Bangalore

Qualitative HPTLC analysis of plant extracts

Auxochromofours Solutions Pvt.Ltd, Bangalore

Funded Projects at the Centre

S.No

Title of Proposal

Funding agency

Names of Investigators

1

Fabrication and Characterization of Bioactive Nano Wafer Enriched with Lyophilized Platelet Rich Fibrin and Nano Hydroxyapatite for Vital Pulp Therapy

DBT call on Nanoscience and Nanotechnology in Dentistry ‑2019 – Sanction letter received from DBT

Dr.Shruthi.N

Dr.C.Pushpalatha

Dr.R.Deveswaran

Dr.Sylvia Mathew

2

In situ gel as cervix plug with spermicidal/​antimicrobial contraceptive (modified condom) 

VGST, Karnataka ‑2019

Ongoing

Dr.B.V.Basavaraj

3

Development of smart polymer bioconjugated with human umbilical cord blood serum proteins and its regeneration potential on human dental pulp cells

ICMR – EMR- 2019 — Ongoing

Dr. Ashmitha K Shetty

Dr.R.Deveswaran

4

Synthesis and Characterisation of a Novel Bio Active Theobromine Composite Resin as a Dental Restorative Material using Nanofiber Technology

ICMR – EMR- 2018 — Ongoing

Dr.Pushpalatha C

Dr.Srikari

Dr.R.Deveswaran

Collaborative projects completed

S.No

Title of the Project

Name of the collaborator

1

Novel biodegradable cover for dental X‑ray as an alternate to plastics

Dr. Sujatha, Dept. of Oral Medicine & Radiology, FDS

2

Estimating the Rate of Elution of Two Antibiotics and curcumin from Tissue Conditioner for Local Drug Delivery 

Dr.Vibha Shetty, Dept. of Prosthodontics, FDS

3

Novel oral sustained release technology using dental materials

4

Development of hydrogel containing fluconazole with tea tree oil

Dr. Harshita Gowda, Dept. of Prosthodontics, FDS

5

Development of patches containing benzocaine with aloe vera

6

Assessment of oregano essential oil as an intra canal medicament against oral pathogen – An in-vitro study

Dr. Pushpalatha.C, Dept. of Pedodontics & Preventive Dentistry, FDS

7

Development of cranberry and grape seed extract as an Intra-canal medicament

8

Development of liquid bandage containing zinger extract

9

Development of Dentipatch

10

Gel containing Hank’s balanced salt

11

Development of propolis oral liquid spray for xerostomia

Dr. Mahantesha, Dept. of Periodontics, FDS

12

Diclofenac sodium coated surgical suture

13

Oral wafers containing ketorolac tromethamine

14

Development of directly compressible calcium carbonate

Mrs. K Shwetha, Dept. of Pharmaceutics

15

Development of sialagogue for xerostomia

16

Disinfectant tablets

17

Analytical method development and validation of Dapagliflozin

Dr.B.V.Suma, Dept. of Pharmaceutical Chemistry, FPH

18

Development of medicated lollipops

Mr.Tanmoy Ghosh, FPH

19

Banana leaf extract powder for wound healing

Patents filed

Indian Patent Applications

  1. Novel Bio Active Theobromine Composite Resin”, Indian Patent Application: 201941054071,
  2. An in-Situ Gel for Corneal Wound Healing”, Indian Patent Application: 201841048755
  3. A Method and Composition of a Pharmaceutical Excipient Using Calcium Carbonate”, Indian Patent Application: 201841049894
  4. Method and Composition to Improve Antibacterial Activity and Surface Micro-Hardness of Root Canal”, Indian Patent Application: 201841049190
  5. An Analgesic Coated Surgical Suture”, Indian Patent Application: 201841048759
  6. Intraoral Liquid Bandage for Sustained Drug Delivery”, Indian Patent Application: 20184105003

DDDC is committed to emerge as a research group of international relevance in the design and development of Novel Drug Delivery Systems adhering to the required norms of contemporary medical treatment modalities.

  • To develop expertize in Drug Delivery in focused research areas: 

Wound Healing System & Neuroregeneration 

  • To develop drugs & delivery Systems for Natural and Synthetic drugs 
  • To develop technologies for Industrial application 
  • To conduct Industrial Training programmes for better understanding on concepts and practices of Pharmaceutical Sciences
  • To promote Innovation and entrepreneurship amongst students
  • To support postgraduate and doctoral students to carry out their research
  • To publish research work in Indexed Journals with good impact factor
  • To develop and pursue joint initiatives for collaboration and partnership with Universities, Research Centres and Pharmaceutical industries 
  • To transfer developed technologies of drug delivery system for commercialization and revenue generation
  • To model, simulate and analyze the human physiological systems and sub-systems from pharmaco-kinetics and pharmaco-dynamics perspective

  • Liquid Chromatography-Mass Spectrometry (LC-MS)
  • Nano spray dryer, electro spinning equipment

  • Micro Labs

    Micro Labs Ltd, Bangalore

  • ITC

    ITC Ltd, Bangalore

  • Lyrus

    Lyrus Life Sciences, Bangalore Ltd

  • Anglob French Drugs

    Anglo French Drugs and Pharmaceuticals, Bangalore

  • Sami Labs

    Sami Labs, Bangalore

  • Aspartika

    Aspartika Biotech, Bangalore

  • Prakruti

    Prakruti Products Pvt. Ltd, Bangalore

  • Arokare

    Arokare Private Ltd, Bangalore

  • Lifecare

    LifeCare Formulations Private Ltd, Puducherry

  • Nandu Chemicals

    Nandu Chemicals Private Ltd, Hubli

  • Embiotic

    Embiotic Laboratories Private Ltd, Bangalore

Contact
Address
Drug Design and Development Centre,
Faculty of Pharmacy, M.S.Ramaiah University of Applied Sciences,
Gnanagangothri Campus, New BEL Road, Bangalore -560054
Ph: 080-23608942 Extn: 29, 9880238650
Email: email hidden; JavaScript is required
ASSOCIATE HEAD
Dr. Sandhya K V
MENTOR
Dr. Premnath Shenoy