Screening of Drugs for Pharmacological Activity and Toxicological Studies


We mainly focus on identifying pharmacologically unique principles from existing traditional remedies for medicinal use pre-clinically. In particular, toxicological, neuro-behaviour related areas we investigate the influence of drugs on components of the nervous system related to learning, memory and drug addiction by understanding the behavioral consequences of experimental intervention on enzyme, neurotransmitters, metabolism and anticancer effect. 

Research Topics

  • Toxicological screening of drugs
  • Antitumor and Cytotoxic effect of test drugs
  • Pharmacokinetic and Pharmacodynamic Interaction studies in animals
  • Wound healing research
  • Neuroprotective studies


  • Analgesiometer
  • Digital Plethysmometer
  • Digital Thermometer
  • Digital stereo taxis
  • T and Y maze for Mouse and Rats
  • Elevated Plus maze for rat and mouse
  • Lagendorff system
  • Organ bath
  • Digital Balance
  • Gel Electrophoresis unit and Blotting Assembly 
  • Lagendorff assembly
  • Vortex shaker
  • Cook’s Pole climbing apparatus
  • Histamine aerosol apparatus

Being Created

  • Deep Freezer
  • Auto-analyzer
  • Piezoplethysmography
  • Animal house (As per CPCSEA guidelines)
  • Incinerator
  • Biochemistry Auto Analyzer 
  • Histopathology unit


  • Evaluation of Neuroprotective Property of Test Drugs Using MPTP Induced Acute Parkinson’s Model 
  • Formulation, characterization and in vitro in vivo evaluation of a polyherbal preparationfor its anti-migraine activity using suitable experimental models
  • Acute, subacute and genotoxicity studies of Siddha medicine
  • In Vivo Antitumor Activity of a Formulation of Indian System of Medicine Using EAC and DAL Cell Lines In Rodents
  • Evaluation of antiosteoporotic activity in rats
  • Invitro and Invivo evaluation of antiurolithiatic effect of test drug
  • Cardioprotective activity of formulations in rats
  • Androgenic and Aphrodisiac effect of drugs on a Everolimus induced infertility in male rats
  • In-Vivo toxicological assessment and Evaluation of Test drug Against Cuprizone Induced Multiple Sclerosis In C57bl/​6j Mice 
  • Evaluation of nootropic effect of test drug by invitro invivo methods 
  • Anti-Ulcer activity in rodents
  • Development of Poly-herbal extract and its evaluation for anti-obesity property in modified diet induced obese model in rats
  • Evaluation of invitro anti-cataract potential of test drug against galactose induced cataract in isolated goat and chick eye
Drug Design and Development Centre,
Faculty of Pharmacy, M.S.Ramaiah University of Applied Sciences,
Gnanagangothri Campus, New BEL Road, Bangalore -560054
Ph: 080-23608942 Extn:29, 9880238650
Email: email hidden; JavaScript is required
Dr. Anbu Jayaraman
Dr. Md Azamathulla
Dr. Kesha Desai
Ms. Gouri Nair